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Johnny Ludvigsson Selected Research

aluminum sulfate (alum)

5/2022Intra-lymphatic administration of GAD-alum in type 1 diabetes: long-term follow-up and effect of a late booster dose (the DIAGNODE Extension trial).
1/2022Association between treatment effect on C-peptide preservation and HbA1c in meta-analysis of glutamic acid decarboxylase (GAD)-alum immunotherapy in recent-onset type 1 diabetes.
1/2022Glutamic acid decarboxylase immunotherapy for type 1 diabetes.
1/2022Intralymphatic GAD-Alum (Diamyd®) Improves Glycemic Control in Type 1 Diabetes With HLA DR3-DQ2.
1/2022Immune response differs between intralymphatic or subcutaneous administration of GAD-alum in individuals with recent onset type 1 diabetes.
10/2021Combined Etanercept, GAD-alum and vitamin D treatment: an open pilot trial to preserve beta cell function in recent onset type 1 diabetes.
1/2021Intralymphatic Glutamic Acid Decarboxylase With Vitamin D Supplementation in Recent-Onset Type 1 Diabetes: A Double-Blind, Randomized, Placebo-Controlled Phase IIb Trial.
1/2021Intralymphatic GAD-alum Injection Modulates B Cell Response and Induces Follicular Helper T Cells and PD-1+ CD8+ T Cells in Patients With Recent-Onset Type 1 Diabetes.
10/2020Efficacy of GAD-alum immunotherapy associated with HLA-DR3-DQ2 in recently diagnosed type 1 diabetes.
1/2020Glutamic Acid Decarboxylase Injection Into Lymph Nodes: Beta Cell Function and Immune Responses in Recent Onset Type 1 Diabetes Patients.
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Johnny Ludvigsson Research Topics

Disease

119Type 1 Diabetes Mellitus (Autoimmune Diabetes)
06/2022 - 01/2002
15Infections
09/2021 - 01/2002
7Type 2 Diabetes Mellitus (MODY)
11/2021 - 03/2006
7Obesity
03/2020 - 10/2006
6Autoimmune Diseases (Autoimmune Disease)
01/2022 - 05/2006
5Celiac Disease (Celiac Sprue)
01/2021 - 03/2010
5Hypoglycemia (Reactive Hypoglycemia)
03/2020 - 05/2006
5Ketosis
02/2018 - 01/2002
5Insulin Resistance
01/2017 - 02/2005
3Inflammation (Inflammations)
01/2021 - 10/2006
3Disease Susceptibility (Diathesis)
01/2021 - 01/2015
3Insulinoma
01/2021 - 01/2017
3Gastroenteritis
01/2017 - 01/2002
2Necrosis
10/2021 - 10/2010
2Juvenile Arthritis (Juvenile Idiopathic Arthritis)
09/2021 - 07/2019
2Birth Weight (Birth Weights)
01/2021 - 11/2013
2Diabetic Ketoacidosis (Ketoacidosis, Diabetic)
01/2020 - 08/2006
2Disease Progression
01/2020 - 01/2017
2Diabetic Retinopathy (Retinopathy, Diabetic)
01/2019 - 05/2009
2Glucose Intolerance
01/2019 - 01/2017
2Diabetes Mellitus
08/2014 - 08/2014
2Pain (Aches)
05/2009 - 03/2002
2Diabetes Complications
05/2009 - 01/2006
1Albuminuria
06/2022
1COVID-19
05/2021
1Hypersensitivity (Allergy)
03/2020
1Lipoma (Lipomata)
03/2020
1Neoplasms (Cancer)
03/2020
1Phobic Disorders (Phobia)
03/2020
1Hyperglycemia
01/2020
1Overweight
01/2020
1Hypertension (High Blood Pressure)
01/2020

Drug/Important Bio-Agent (IBA)

37Insulin (Novolin)FDA Link
11/2021 - 03/2002
31AutoantibodiesIBA
01/2021 - 04/2002
23Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA
01/2022 - 03/2006
23C-PeptideIBA
01/2022 - 11/2006
22aluminum sulfate (alum)IBA
05/2022 - 10/2008
12AntigensIBA
07/2021 - 06/2008
9AutoantigensIBA
01/2022 - 11/2006
9Glucose (Dextrose)FDA LinkGeneric
11/2021 - 01/2002
9AntibodiesIBA
01/2021 - 04/2002
7Zinc Transporter 8IBA
01/2021 - 08/2011
7Glutens (Glutelin)IBA
08/2014 - 03/2006
6CytokinesIBA
01/2014 - 02/2005
5Biomarkers (Surrogate Marker)IBA
01/2022 - 02/2013
5Vitamin DFDA LinkGeneric
10/2021 - 02/2007
5HLA-DQ Antigens (HLA-DQ)IBA
01/2021 - 10/2012
5AluminumIBA
01/2021 - 01/2011
5HLA Antigens (Human Leukocyte Antigens)IBA
01/2019 - 08/2007
4Anti-Bacterial Agents (Antibiotics)IBA
09/2021 - 04/2014
4Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2021 - 02/2005
4Tyrosine (L-Tyrosine)FDA Link
01/2021 - 02/2005
4Amino AcidsFDA Link
11/2020 - 03/2016
4VaccinesIBA
08/2017 - 05/2009
3LipidsIBA
06/2022 - 05/2009
3teplizumabIBA
11/2019 - 08/2011
3hydroxide ionIBA
03/2017 - 01/2011
3Immunoglobulin G (IgG)IBA
01/2017 - 10/2010
3Proteins (Proteins, Gene)FDA Link
10/2006 - 04/2006
2CholesterolIBA
06/2022 - 01/2020
2Biological ProductsIBA
01/2022 - 01/2017
2HLA-DRB1 Chains (HLA DRB1)IBA
07/2021 - 01/2019
2Protein Glutamine gamma Glutamyltransferase 2IBA
01/2021 - 01/2018
2HLA-DQA1 antigen (HLA DQA1)IBA
11/2020 - 01/2020
2Blood Glucose (Blood Sugar)IBA
03/2020 - 01/2002
2HLA-DRB3 Chains (HLA DRB3)IBA
01/2019 - 03/2016
2Amyloid (Amyloid Fibrils)IBA
01/2017 - 01/2014
2MicronutrientsIBA
11/2016 - 03/2012
2Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
01/2014 - 02/2012
2Protein Isoforms (Isoforms)IBA
02/2012 - 10/2008
2InterleukinsIBA
10/2010 - 04/2006
1oxidized low density lipoproteinIBA
06/2022
1Triglycerides (Triacylglycerol)IBA
06/2022
1Immune Checkpoint ProteinsIBA
01/2022
1RNA (Ribonucleic Acid)IBA
11/2021
1Etanercept (Enbrel)FDA Link
10/2021
1HLA-DR4 Antigen (HLA DR4 Antigen)IBA
07/2021
1Mitochondrial DNA (mtDNA)IBA
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1Pharmaceutical PreparationsIBA
03/2020
1InsulinsIBA
03/2020
1Phospholipids (Phosphatides)FDA LinkGeneric
02/2020
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
02/2020
1LDL Lipoproteins (beta Lipoproteins)IBA
01/2020
1GlucokinaseIBA
01/2020
1P-2 (P 2)IBA
01/2020
1HDL LipoproteinsIBA
01/2020
1Heavy MetalsIBA
07/2019
1casein hydrolysateIBA
01/2018
1Dietary ProteinsIBA
01/2018
1Caseins (Casein)FDA Link
01/2018

Therapy/Procedure

12Therapeutics
10/2021 - 03/2005
5Glycemic Control
01/2022 - 05/2009
3Immunotherapy
01/2022 - 10/2020
3Immunomodulation
01/2022 - 03/2009
3Injections
05/2012 - 03/2002
2Intralymphatic Injections
01/2017 - 01/2017
2Gluten-Free Diet
02/2014 - 05/2011
1Precision Medicine
01/2022
1Critical Care (Surgical Intensive Care)
05/2021